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The effect of alpha-1-acidic glycoprotein on neutrophil chemiluminescence and lipid peroxidation in experimental thermal trauma

Salomatin, V.V.; Liutov, A.G.; Enikeeva, S.A.; Charnaia, L.F.; Zurochka, A.V.; Dolgushin, I.I.

Voprosy Meditsinskoi Khimii 39(3): 24-26

1993

ISSN/ISBN: 0042-8809
PMID: 8333183
Document Number: 407485
Induced chemoluminescence of neutrophils was distinctly inhibited both in intact mice and the animals with thermal injury after administration of acid alpha 1-glycoprotein. At the same time, the glycoprotein decreased the rate of thermal burn-induced activation of lipid peroxidation in rat blood, skin and liver tissue. Antioxidative and therapeutic effects of acid alpha 1-glycoprotein in burns appear to be related to regulation of neutrophil activity.

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