Interactions of vitamin D with sodium zeolite A in rats from low and adequate vitamin D colonies

Keenan, M.J.; Hegsted, M.; Wozniak, P.J.; Bott, J.D.; Reisenauer, A.

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 62(3): 228-232

1992


ISSN/ISBN: 0300-9831
PMID: 1335443
Document Number: 404266
Weanling rats (21 days old) from either a low vitamin D colony or an adequate vitamin D colony fed either a vitamin D adequate or a vitamin D deprived AIN-76A purified diet were used as a model to investigate interactions of vitamin D status with dietary sodium zeolite A (100 mg/kg body wt/day). Rats with adequate or replete vitamin D status had greater overall body weight gain, dry tibia weights and femur densities and ash weights than rats fed a vitamin D deprived diet. Addition of sodium zeolite A to the diets did not have an effect on plasma calcium, body weight gain or on femur density, ash and percent ash. Dietary sodium zeolite A increased total tibia fat in rats fed the vitamin D adequate diet and decreased total tibia fat in rats fed the vitamin D deprived diet. This effect of sodium zeolite A appeared to be beneficial to bone status in the groups fed adequate vitamin D, since these treatment groups had higher, although not significant, dry tibia weights with and without fat.

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