Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations
Pawlicki, R.; Knychalska-Karwin, Z.; Stankiewicz, D.; Jakób-Dolezal, K.; Karwan, T.
Folia Histochemica et Cytobiologica 30(2): 75-78
1992
ISSN/ISBN: 0239-8508 PMID: 1483537 Document Number: 403182
Distribution of calcium and phosphorus was investigated with quantitative and qualitative methods in teeth of rats chronically treated with low doses of corticosteroids for 3 generations. In animals from 2nd and 3rd generation, scanning electron microscopy revealed focal lesions in enamel and dentin. The disturbances of the mineral metabolism in teeth of corticosteroid-treated rats were also reflected by abnormal calcium and phosphorus content in enamel and dentin, as assessed by X-ray microanalysis.