Toxicity of chongqing acid fogwater on rabbit alveolar macrophages in vitro
Shu, W.Q.; Zhuo, J.B.
Zhonghua Yu Fang Yi Xue Za Zhi 26(4): 206-208
1992
ISSN/ISBN: 0253-9624 PMID: 1302192 Document Number: 401746
We collected acid fogwater on a fogday and observed its toxic effects on rabbits' pulmonary alveolar macrophages (AM) in vitro. the fogwater was diluted into 4 concentrations: 1, 1/10, 1/100, and 1/1000 of the original fogwater and the exposure time was 12 hours. The results showed that both the AM's viability and the phagocytic capacity were depressed significantly, but the AM's lysosomal enzyme sbd acid phosphatase activity was found to be stimulated to increase. All these changes were directly correlated with the degree of pollution of the fogwater. Of these three toxicity indices, the most sensitive one was the change of AM's phagocytic capacity.