Subcellular distribution of the neutral proteinases of rabbit alveolar macrophages

Andrew, P.W.; Hughes, K.T.; Davies, M.; Peters, T.J.

Cellular and Molecular Biology 29(4): 315-321

1983


ISSN/ISBN: 0145-5680
PMID: 6354449
Document Number: 199187
Alveolar macrophages from normal and BCG-vaccinated rabbits have proteolytic activity against azocasein and hydrolyze synthetic substrates for the detection of cathepsin G and cathepsin B. These activities were located in granules using latency studies and analytical fractionation by isopycnic centrifugation of macrophage homogenates.

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