Langerhans-cell histiocytosis of the vulva. General review and a case history
Saurel, J.; Savin de Larclause, A.M.; Mercier, M.; Rabreau, M.; Tessier, D.; Clément, A.
Journal de Gynecologie Obstetrique et Biologie de la Reproduction 21(8): 897-901
1992
ISSN/ISBN: 0368-2315 PMID: 1491133 Document Number: 401393
Localisation of Langerhans' cell histiocytosis (HCL) is rare. In solitary form the prognosis for this pathology is good, if the tumour occurs in a woman of 36 years of age. (In this case the woman's age was 91) The appearances may be misleading clinically. The diagnosis is made by histological examination of P-S 100 positive cells and by finding Birbeck's granules on electron microscopy. Treatment may be surgical or as in our case medical.