Antibody titer to streptococcal and staphylococcal L-form in Behçet's disease and other uveitis
Namba, K.; Ogawa, T.; Nishiyama, Y.; Sawada, K.
Nippon Ganka Gakkai Zasshi 96(10): 1286-1289
1992
ISSN/ISBN: 0029-0203 PMID: 1442354 Document Number: 400117
The antibody titer in serum to Streptococcus pyogenes L-form and Staphylococcus aureus L-form were determined by enzyme-linked immunosorbent assay in 28 patients with Behcet's disease, 31 patients with other uveitis (sarcoidosis: 10, Harada's disease: 5, tuberculosis: 4, rheumatoid arthritis: 4, lues: 2, juvenile rheumatoid arthritis: 2, herpes simplex: 2, trauma: 2) and 16 healthy normal controls. All L-forms were induced by the penicillin disk method. The antibody titer to Streptococcus pyogenes L-form in Behcet's disease was lower than that of other cases of uveitis and controls, and showed significant differences between controls, rheumatoid arthritis, sarcoidosis, tuberculosis and Harada's disease by the Student's t-test. The antibody titer to Staphylococcus aureus L-form in Behcet's disease showed no difference between controls and other cases of uveitis. In each uveitis and controls, and between active and inactive stages of all uveitis, there were no differences between titers. In Behcet's disease, antibody formation to Streptococcus pyogenes L-form may be specifically disturbed.