Titer of anti-streptococcal antibody in Behçet's disease
Namba, K.
Nippon Ganka Gakkai Zasshi 92(2): 269-273
1988
ISSN/ISBN: 0029-0203 PMID: 3291579 Document Number: 309210
The titers of anti-streptococcal antibodies were studied in Behcet' disease. The serum antiboy titer to streptococcal autoclaved extracts was determined by enzyme-linked immunosorbent assay. The titer in 26 patients was significantly lower than that in 36 normal controls (p 0.05, Student's t-test). The cell anti-streptolysin O titer was determined by the method of Matsumura et al. The titer showed no significant difference between 70 patients and 43 controls. There was no significant difference in the titers between the active and inactive stages of the disease. These data suggest that anti-streptococcal antibodies cannot be produced sufficiently in Behcet's disease. The roles played by susceptibility to streptococci, streptococcal pyrogenic exotoxin, streptococcal L-form were discussed.