Measurement of retinal circulation in uveitis of Behçet's and Harada's disease
Sugihara, I.
Nippon Ganka Gakkai Zasshi 93(6): 705-713
1989
ISSN/ISBN: 0029-0203 PMID: 2816579 Document Number: 339691
In order to investigate retinal circulation in patients with Behcet's disease and Harada's disease, we divided 27 patients into three groups; Behcet's groups (8 patients), Harada's group (8 patients) and the control group (11 normal subjects). By means of video-densitometric image analysis of fluorescein angiography, we measured the buildup time (BT), time constant of washout rate (TC) and mean circulation time (MCT) for both the retinal artery and vein. The results were as follows: (1) The BT in Behcet group was slightly prolonged compared to that in the control group, while the BT in Harada's disease was shorter than that in the control group. (2) The TC in both the Behcet's and Harada's groups was significantly prolonged compared to that in the control group. (3) The MCT in both Behcet's and Harada's groups was not significantly different from that in the control group. These results suggest that Behcet's disease cases may have normally and compensatory retinal circulation, whatever vasculitis occurs on retinal vassels. On the other hand, chroiditis in Harada's disease has no influence on retinal circulation.