Thiochrome inhibition of alcohol dehydrogenase
Petrov, S.A.
Ukrainskii Biokhimicheskii Zhurnal 64(6): 91-94
1992
ISSN/ISBN: 0201-8470 PMID: 1488820 Document Number: 400004
It is shown that thiochrome inhibits alcohol dehydrogenase. Thiochrome is able to be bound with alcohol dehydrogenase more quickly than other thiamine metabolites. This process is specific and has common features with the process of NAD binding by this enzyme. The inhibition of alcohol dehydrogenase by thiochrome is concurrent to NAD. The constant of alcohol dehydrogenase inhibition by thiochrome is 3.9 x 10(-5) M.
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