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Study of foetal antigen in haematological malignancy

Mukherjee, N.; Chatterjee, D.; Biswas, T.K.; Sarkar, M.

Journal of the Association of Physicians of India 40(6): 384-387

1992

ISSN/ISBN: 0004-5772
PMID: 1452563
Document Number: 398165
Forty patients with different varieties of leukaemia and lymphoma were studied before and after therapy. Red cells and lymphocytes from each patient were tested for foetal antigen by lectin-agglutination test. The antigen was detectable on red cells in all untreated cases, the highest titre being found in chronic myeloid leukaemia. The titre showed significant reduction after treatment in all cases. We conclude that foetal antigen on red cells is a useful diagnostic aid in haematological malignancy and is a good indicator of the outcome of therapy.

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