Risk factor for acute viral hepatitis: a case-control study
Yan, Y.
Zhonghua Liu Xing Bing Xue Za Zhi 13(1): 5-8
1992
ISSN/ISBN: 0254-6450 PMID: 1581957 Document Number: 396553
One hundred and sixty-two patients with acute viral hepatitis in two hospitals were studied between January and December, 1988. The risk factors, epidemiologic features and prognosis of those patients were investigated by case-control and follow-up study. Among the 162 patients, 37.0% were hepatitis A, 40.7% were hepatitis B, and 19.8% were non-A, non-B hepatitis; there were 4 cases of mixed infection and 3 cases of fulminant hepatitis not included in the study. By simple case-control and logistic regression analysis, the patients of hepatitis A more often had history of personal contact with hepatitis cases (OR = 10.56) and of ingesting some contaminated foods (OR = 4.25); hepatitis B more often had history of personal contact with hepatitis cases in their families or elsewhere (OR = 5.66; OR = 4.30 respectively); and hepatitis NANB more often had history of previous clinical hepatitis episode (OR = 6.56), of personal contact with cases of hepatitis (OR = 3.82) and of receiving a blood transfusion (OR = 16.67). Among hepatitis A, B and NANB cases, sequelae of chronic hepatitis after acute phase were found in 0%, 12.1% and 16.7% of cases, respectively.