Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study
Tanwandee, T.; Piratvisuth, T.; Phornphutkul, K.; Mairiang, P.; Permpikul, P.; Poovorawan, Y.
Journal of the Medical Association of Thailand 89(Suppl 5): S79-S83
2006
ISSN/ISBN: 0125-2208 PMID: 17722300 Document Number: 14743
To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated by using conditional logistic regression. The final multivariable model included only the following independent HCVrisk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection.