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Effects of blood platelets on generation of free radicals by leukocytes

Kogan, A.K.; Ershov, V.I.; Sokolova, I.I.; Alekperova, G.R.

Biulleten' Eksperimental'noi Biologii i Meditsiny 113(6): 582-584

1992

ISSN/ISBN: 0365-9615
PMID: 1446021
Document Number: 396377
The paper is concerned with studies on generation of free radicals by donor leukocytes in plasma rich or poor in platelets. NBT test and chemiluminescence were employed. Platelets are shown to inhibit generation of free radicals. Changes in free radicals generation were studied under stimulation by zymosan and addition of washed platelet fraction. The conclusion is made that platelets inhibit leukocyte generation of free radicals by adsorption factors necessary for this process from plasma.

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