Guillain-Barré syndrome, pregnancy, and plasmapheresis
Clifton, E.R.
Journal of the American Osteopathic Association 92(10): 1279-1282
1992
ISSN/ISBN: 0098-6151 PMID: 1459875 Document Number: 394733
The case of Guillain-Barré syndrome (acute inflammatory polyradiculoneuritis) in pregnancy reported here brings the total reported number to 35. The patient had plasmapheresis with no maternal or fetal complications. She did not require mechanical ventilation. This is only the fifth reported case of Guillain-Barré syndrome in the gravid patient involving plasmapheresis. There have been no controlled studies assessing the safety of plasmapheresis in the pregnant patient with the disorder. The possible risks of the procedure need to be weighed against the high maternal mortality rate in such a patient.