Prognosis in Guillain-Barré syndrome
Winer, J.B.; Hughes, R.A.; Greenwood, R.J.; Perkin, G.D.; Healy, M.J.
Lancet 1(8439): 1202-1203
1985
ISSN/ISBN: 0140-6736 PMID: 2860398 Document Number: 243266
The case-records of 71 patients from previous therapeutic trials were used to determine features in clinical presentation that might be useful in predicting the outcome of the Guillain-Barré syndrome. The major features adversely affecting prognosis were severe maximum deficit requiring ventilation and failure to improve within 3 weeks of reaching peak deficit. The risk of poor outcome in a patient who required ventilation and failed to improve within 3 weeks was 86%.