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Liver and serum lysosomal enzymes activity during zymosan-induced inflammation in mice

Safina, A.F.; Korolenko, T.A.; Mynkina, G.I.; Dushkin, M.I.; Krasnoselskaya, G.A.

Agents and Actions. Supplements 38: 370-375

1992

ISSN/ISBN: 0379-0363
PMID: 1462869
Document Number: 392774
Liver and serum lysosomal enzymes (acid glucosidases and cysteine proteinases) during zymosan-induced stimulation of MPS or MPR depression induced by GdCl3 have been studied. Zymosan was used as a model for study of inflammation in vivo. The development of inflammation induced by zymosan was followed by increase activity of macrophage activation markers - beta-N-acetylglucosaminidase (NAGlu) and beta-N-acetylgalactosaminidase (NAGal) in liver and serum. There was enhance of liver cysteine proteinases activity. Similar, less prominent (partly) data were obtained during macrophage depression induced by GdCl3.

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