The comparison of dynamics in humoral responses in health personnel after vaccination against hepatitis B using Engerix B and Gen-H-B-vax
Rokossowski, H.; Juszczyk, J.
Przeglad Epidemiologiczny 46(4): 263-269
1992
ISSN/ISBN: 0033-2100 PMID: 1305774 Document Number: 392015
The dynamics of humoral response in two groups of health care workers vaccinated according to the schedule 0, 1, 6 months, using two different recombinant vaccines has been comprised. In the group of persons vaccinated with Engerix B, 63 completed the full cycle of vaccination. Protective titer of anti-HBs (> or = 10 IU/L) was obtained in 93.6% of vaccinated. In the group of persons vaccinated with Gen-H-B-Vax, 62 completed the full cycle of vaccination, and protective titer of anti-HBs amounted to 90.3% of vaccinated. The humoral response on the protective level in both groups was not statistically different. However, the percentage of the persons with very high anti-HBs titers (10,000 and more IU/L) was higher after Engerix B.