Immunogenicity of a recombinant yeast-derived hepatitis B vaccine (Engerix B) in children
Moyes, C.; Milne, A.
New Zealand Medical Journal 101(843): 162-164
1988
ISSN/ISBN: 0028-8446 PMID: 2965799 Document Number: 319584
Eighty-one children seronegative for markers of hepatitis B virus infection aged 0-10 years received 10 micrograms of a yeast-based hepatitis B vaccine (Engerix B) at 0, 1, and 6 months. Eighty subjects responded with a geometric mean titre of 7640 IU/L one month after the third dose. All seroconverters produced high level of antibodies regardless of age, race, or sex. It is concluded that Engerix B used in the dose and schedule described is highly immunogenic.
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