Influence of reagent composition on atypical pseudocholinesterase activity measurement: comparison of a manual and an automated method and implications for routine
Krull, N.B.; Kropf, J.; Gressner, A.M.
European Journal of Clinical Chemistry and Clinical Biochemistry 30(9): 545-546
1992
ISSN/ISBN: 0939-4974 PMID: 1457618 Document Number: 391276
In determining activities of atypical pseudocholinesterase using a Hitachi 737 and a Cobas Bio analyser, respectively, we repeatedly found discrepancies between the enzyme activities measured by both instruments which were presumably due to differences in the reagent composition (Hitachi 737: Boehringer Mannheim Automated Analysis for BM/Hitachi Systems; Cohas Bio: Boehringer Mannheim Monotest). We consider the present results all components of the chemical systems they produce and as a warning of users when interchanging apparently identically composed sets of reagents.