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Topical administration of cyclosporine for treatment of keratoconjunctivitis sicca in dogs

Morgan, R.V.; Abrams, K.L.

Journal of the American Veterinary Medical Association 199(8): 1043-1046

1991

ISSN/ISBN: 0003-1488
PMID: 1748607
Document Number: 387460
Sixty dogs with chronic keratoconjunctivitis sicca were treated by topical administration of 2% cyclosporine twice daily. Causes and duration of keratoconjunctivitis varied. Tear production improved in 75 of 100 eyes, and corneal pigmentation decreased in 45 of 67 eyes. Six factors were evaluated to determine their influence on treatment outcome. The only significant variable was the initial Schirmer tear test value. Side effects were few. Evidence of burning in response to application of cyclosporine resolved with change in the formulation of the topical solution.

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Sansom, J.; Barnett, K.C.; Neumann, W.; Schulte-Neumann, A.; Clerc, B.; Jegou, J.P.; de Haas, V.; Weingarten, A. 1995: Treatment of keratoconjunctivitis sicca in dogs with cyclosporine ophthalmic ointment: a European clinical field trial Veterinary Record 137(20): 504-507
Iishi, A. 1986: Studies on a staining test for keratoconjunctivitis sicca. II. Quantitative analysis of the fluorescein test and other clinical features in keratoconjunctivitis sicca Nippon Ganka Gakkai Zasshi 90(10): 1268-1273
Sainz De La Maza Serra M; Simón Castellvi C; Kabbani, O. 2000: Nonpreserved topical steroids and lacrimal punctal occlusion for severe keratoconjunctivitis sicca Archivos de la Sociedad Espanola de Oftalmologia 75(11): 751-756
Sansom, J.; Barnett, K.C.; Long, R.D. 1985: Keratoconjunctivitis sicca in the dog associated with the administration of salicylazosulphapyridine (sulphasalazine) Veterinary Record 116(15): 391-393
Kosrirukvongs, P.; Luengchaichawange, C. 2004: Topical cyclosporine 0.5 per cent and preservative-free ketorolac tromethamine 0.5 per cent in vernal keratoconjunctivitis Journal of the Medical Association of Thailand 87(2): 190-197
Lettow, E.; Hildebrand, B. 1977: Keratoconjunctivitis sicca in the dog Tierarztliche Praxis 5(3): 351-368
Wilkie, D.A.; Wolf, E.D. 1990: Sulfonamides and keratoconjunctivitis sicca Journal of the American Veterinary Medical Association 196(4): 521-522
Slatter, D.H.; Bryan, G.M. 1973: Keratoconjunctivitis sicca due to phenazopyridine HCl Journal of the American Veterinary Medical Association 162(6): 426 Passim
Avisar, R.; Savir, H. 1988: Our further experience with bromhexine in keratoconjunctivitis sicca Annals of Ophthalmology 20(10): 382
Pals, H.; Madsen, F.; Frølund, L.; Svendsen, U.G.; Faurschou, P. 1987: Attacks of dyspnoea in a patient with keratoconjunctivitis sicca European Journal of Respiratory Diseases 70(1): 65-66
Singla, R.K.; Jain, I.S.; Sehgal, S.; Gupta, S.D. 1974: Clinical and immunological aspects of keratoconjunctivitis sicca Indian Journal of Ophthalmology 22(4): 10-15
Collins, B.K.; Moore, C.P.; Hagee, J.H. 1986: Sulfonamide-associated keratoconjunctivitis sicca and corneal ulceration in a dysuric dog Journal of the American Veterinary Medical Association 189(8): 924-926
Iudina, I.V.; Malakhova, L.A. 1983: Ocular tension in keratoconjunctivitis sicca in Sjögren's syndrome Vestnik Oftalmologii 5: 9-11
Yu, G.-Y. 2010: The guideline for microvascular autologous submandibular gland transfer for severe cases of keratoconjunctivitis sicca Zhonghua Kou Qiang Yi Xue Za Zhi 45(7): 391-393
Safonova, T.N.; Ovchinnikov, A.N.; Fedorov, A.A.; Polunin, G.S. 1998: Keratoconjunctivitis sicca in Sjögren's syndrome: diagnostic significance of relative protein composition of tears Vestnik Oftalmologii 114(2): 40-42
Prause, J.U.; Bjerrum, K.; Johansen, S. 1994: Effect of sodium sucrose-sulfate on the ocular surface of patients with keratoconjunctivitis sicca in Sjögren's syndrome Advances in Experimental Medicine and Biology 350: 691-696
Van Bijsterveld, O.P. 1990: Diagnosis and differential diagnosis of keratoconjunctivitis sicca associated with tear gland degeneration Clinical and Experimental Rheumatology 8(Suppl 5): 3-6
Iishi, A. 1985: Studies on staining test for keratoconjunctivitis sicca. I. Quantization of fluorescein test by image analysis Nippon Ganka Gakkai Zasshi 89(12): 1359-1365
Nelson, J.D.; Friedlaender, M.; Yeatts, R.P.; Yee, R.; McDermott, M.; Orlin, S.; Gallagher, S.C.; Shrotriya, R.C. 1998: Oral pilocarpine for symptomatic relief of keratoconjunctivitis sicca in patients with Sjögren's syndrome. the MGi PHARMA Sjögren's Syndrome Study Group Advances in Experimental Medicine and Biology 438: 979-983
De Prost, Y.; Teillac, D.; Paquez, F.; Carrugi, C.; Bachelez, H.; Touraine, R. 1988: Treatment of severe alopecia areata by topical applications of cyclosporine: comparative trial versus placebo in 43 patients Transplantation Proceedings 20(3 Suppl 4: 112-113