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Platelet aggregation in different clinical variants of the course of ischemic heart disease

Sopina, N.V.

Klinicheskaia Meditsina 69(10): 40-41

1991

ISSN/ISBN: 0023-2149
PMID: 1766213
Document Number: 385734
Dynamic examination for ADP-induced platelet aggregation was performed in coronary patients with angina pectoris, microfocal or macrofocal uncomplicated myocardial infarction, recurrent infarction, cardiogenic shock. Healthy subjects served as control. The unidirectional trend was revealed: a decrease in aggregation and disaggregation capacity of platelets most evident in complicated coronary heart disease. This seems to result from initial platelet hyperactivation and subsequent depletion. Platelet hemostasis correction is feasible under early and accurate diagnosis of the above impairments.

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