The persistence of the distemper virus in continuous human cells
Marasinskaia, E.I.; Bogomolova, N.N.; Burgasova, M.P.; Dorofeev, V.M.
Voprosy Virusologii 36(2): 144-146
1991
ISSN/ISBN: 0507-4088 PMID: 1715629 Document Number: 385656
Two cultures chronically infected with distemper virus (HEP-2 and L-41) were obtained. The cultures produced a small-plaque cell-associated virus and a virus-specific antigen which was demonstrated by the fluorescence antibody technique in 40%-60% of the cells. The chronically infected cells produced interferon as judged by their resistance to superinfections with heterologous viruses. The virus-carrier state was characterized by temperature sensitivity.