Multiple malignant tumors in Recklinghausen's neurofibromatosis
Crăiţoiu, S.; Enculescu, A.
Oftalmologia 35(2): 67-71
1991
ISSN/ISBN: 1220-0875 PMID: 1811755 Document Number: 384946
The case of a woman aged 77 years, with cutaneous manifestations of neurofibromatosis, is described, in whom cutaneous fibromas with malignant degeneration, displaying an aspect of fibrosarcoma, were detected. The anatomopathological examination shows fibroblastic type tumoral cells, of a globulous aspect, as well as the presence of cell monstruosities with numerous mitoses, among nervous cells and amyelinic fibers are found. Malignization occurs in Recklinghausen's neurofibromatosis at a rate up to 20% of cases.