Thiocyanate--a pathogenetic factor in cystic fibrosis (mucoviscidosis) ?
Weuffen, W.; Hein, J.; Below, H.; Gülzow, H.U.
Padiatrie und Grenzgebiete 30(3): 205-210
1991
ISSN/ISBN: 0030-932X PMID: 2067870 Document Number: 384947
Thiocyanate (SCN-) concentrations in serum samples of 32 cystic fibrosis (CF) patients, 30 controls as well as 23 heterozygotes (parents of CF patients) were investigated, because SCN- influenced viscosity of secretions, membrane functions as well as nonspecific and specific defense processes. CF patients showed little smaller SCN- serum levels, but the differences were not statistically significant. There were remarkable smaller values for CF patients with most serious clinical conditions due to severe pulmonary changes.