On the putative mechanism of induction and regulation of melanogenesis by L-tyrosine
Howe, J.; Costantino, R.; Slominski, A.
Acta Dermato-Venereologica 71(2): 150-152
1991
ISSN/ISBN: 0001-5555 PMID: 1675526 Document Number: 384677
The stimulation of melanogenesis by L-tyrosine in hamster melanoma is several-fold higher than that by norepinephrine, epinephrine, clonidine and isoproterenol and absent in the case of tyramine dopamine and phenylephrine. Therefore, the melanogenic effect of L-tyrosine in hamster melanoma follows a different pathway than that linked to the activation of dopaminergic and adrenergic receptors.