The modelling of a persistent parainfluenza infection
Ukbaeva, T.D.; Karal'nik, B.V.; Ismagulov, A.T.
Voprosy Virusologii 36(5): 387-389
1991
ISSN/ISBN: 0507-4088 PMID: 1666475 Document Number: 381195
A model of parainfluenza persistent infection was developed in guinea pigs, based on the use of the suckling-adapted virus and an immunosuppressor cyclophosphan. The latter increased the titre of virus and its antigen and duration of their detection in the organs, but the dynamics of these findings was different, and also delayed the time of appearance and slightly prolonged the period of detection of antibody.
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