Distribution of type a and type B EBV in patients with nasopharyngeal carcinoma
Shu, C.H.; Liu, W.T.; Chang, Y.S.; Liang, C.L.; Liu, S.T.; Lin, C.Z.; Chang, P.
Zhonghua Yi Xue Za Zhi 48(6): 427-430
1991
ISSN/ISBN: 0578-1337 PMID: 1664280 Document Number: 380483
The subtypes of Epstein-Barr virus (EBV) according to EBNA 2 genes were investigated in 53 nasopharyngeal carcinoma (NPC) biopsies in Taiwan by polymerase chain reaction (PCR) and by Southern blot hybridization method. EBV DNA was found present in all NPC biopsies. Type A was the predominant type and comprised of 94.3% of the EBV of NPC. Type B or coinfection of type A and type B comprised of only 3.8% and 1.9% respectively.
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