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Serum factors regulating macrophage migration in chronic cicatricial stenosis of larynx and trachea in children

Shuster, A.M.; Suslov, A.P.; Onufrieva, E.K.

Vestnik Otorinolaringologii 2: 40-44

1991

ISSN/ISBN: 0042-4668
PMID: 2048252
Document Number: 379773
Many children with chronic cicatricial stenosis of the larynx and trachea showed a high activity of the factor stimulating macrophage migration in vitro (MSF). The high MSF level is typical of patients with large scars in tissues rich in cellular elements. The MSF predominance was to a certain extent correlated with abnormal responses to surgical intervention. This was indicated by poor results of surgical treatment if the MSF was low before and immediately after it. With normal MSF the treatment was effective in at least 50% of cases. The therapeutic effectiveness was correlated with MSF variations at an early postoperative stage.

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