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Morphological and structural aspects of solid drug forms

Bettinetti, G.

Bollettino Chimico Farmaceutico 130(3): 85-88

1991

ISSN/ISBN: 0006-6648
PMID: 1892610
Document Number: 378957
As a follow-up to a previous article, where the characteristics of the solid state and the X-ray properties and pharmaceutical applications were described ("X-rays, diffractometry in the analysis of drugs and pharmaceutical forms", Boll. Chim. Farm. 128, 149; 1989), the Author has more specifically considered the so-called "variants" of a drug's solid state, which can be employed in the dosage forms (polymorph, solvate, crystalline habitus, amorphous). In addition, mention is made of drugs' isomorphism and the difference between a polymorphic solvate and the polymorphism of a solvate is clearly stressed.

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