Immunodepressants used in immune system pathology. I. Cyclosporin, cyclophosphane, azathioprine and mercaptopurine
Napolov, I.K.; Borisov, K.B.
Farmakologiia i Toksikologiia 54(4): 80-87
1991
ISSN/ISBN: 0014-8318 PMID: 1786839 Document Number: 376836
The data on immunodepressants most commonly used in the Soviet Union in the diseases caused by disorders in normal function of the immune system are presented. Such drugs as cyclosporine A, cyclophosphan, azatioprine, 6-mercaptopurine are considered. Emphasis is given to the mechanism of the primary pharmacological response of the drugs to the immunocompetent cells, the grounding of their clinical use, dosage and mechanisms of possible side effects.
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