Isochromosome 17q as the sole alteration in 2 patients with a myelodysplastic syndrome and its relation to myeloperoxidase activity
Solé, F.; Pérez, A.; Woessner, S.; Olmedo, E.; Florensa, L.; Sans, J.
Sangre 36(4): 323-325
1991
ISSN/ISBN: 0036-4355 PMID: 1663663 Document Number: 376357
Two patients diagnosed of myelodysplastic syndrome with an isochromosome i (17q) as the only chromosomal alteration are presented. The MAC method (i.e., morphology, antibodies, chromosomes) was applied in the study of one of the patients, it being found that all the myeloperoxidase-positive cells carried the i (17q) anomaly. Such finding might suggest that those patients with i (17q) as the only chromosomal alteration could have specific clinical and cytological features.