The activity of neutrophil myeloperoxidase in patients with Hodgkin's disease
Dabrowska, M.; Kemona, H.; Prokopowicz, J.; Dabrowski, A.; Kiluk, S.
Folia Haematologica 117(6): 817-821
1990
ISSN/ISBN: 0323-4347 PMID: 1713888 Document Number: 362147
Neutrophil myeloperoxidase activity has been studied in twenty one patients diagnosed with Hodgkin's disease. The presented data indicate no differences in total MPO activity, whereas we observed some differences in the percentage of granulocytes with different degree of scores. Changes in the intensity of reaction may indicate the possibility of exocytosis as a mechanism releasing MPO from the cell to the surrounding area. In peripheral, circulating neutrophils, such a phenomenon seems to be of no avail and may disorganize anti-cancer defense.