Warning: fatal reaction to the use of fibrin glue in deep hepatic wounds. Case reports

Berguer, R.; Staerkel, R.L.; Moore, E.E.; Moore, F.A.; Galloway, W.B.; Mockus, M.B.; Berguer, R; Staerkel, R.L; Moore, E.E; Moore, F.A; Galloway, W.B; Mockus, M.B

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Warning: fatal reaction to the use of fibrin glue in deep hepatic wounds. Case reports

Berguer, R.; Staerkel, R.L.; Moore, E.E.; Moore, F.A.; Galloway, W.B.; Mockus, M.B.

Journal of Trauma 31(3): 408-411

1991

ISSN/ISBN: 0022-5282

PMID: 2002531

Document Number: 372526

Two cases of severe hypotension following the use of fibrin glue for hemostasis in hepatic injuries are reported. A systemic reaction to bovine thrombin via large venous lacerations is suspected. A preliminary animal study supports this hypothesis. Caution is advised in the use of fibrin glue for hemostasis in deep hepatic wounds.