Cathepsin D inhibitor from potato reverses inhibition of collagen biosynthesis in wounded skin of rats with experimental diabetes

Pałka, J.; Sobolewski, K.; Bańkowski, E.

Acta Biochimica Polonica 38(1): 115-118

1991


ISSN/ISBN: 0001-527X
PMID: 1796692
Document Number: 371850
It was found that streptozotocin-induced diabetes is accompanied by increased proteolytic activity and decreased collagen biosynthesis in rat skin wounds. External application of cathepsin D inhibitor from potatoes normalized the proteolytic activity and restored collagen biosynthesis in wounded skin of these animals.

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