In vivo imaging of benzodiazepine receptors of the central type
Bartenstein, P.; Schober, O.
Wiener Klinische Wochenschrift 103(21): 647-648
1991
ISSN/ISBN: 0043-5325 PMID: 1663299 Document Number: 370922
Two main types of benzodiazepine receptors exist in the human brain, the central receptor type being responsible for the classical actions of the compound. Although interesting findings have been obtained in epilepsy, hepatic encephalopathy and other clinical conditions, a relevant clinical indication for the in vivo imaging of receptor binding has not yet been defined, with the possible exception of the Lennox-Gastant syndrome.
Document emailed within 1 workday
Related Documents
Szmigielska, H.; Szmigielski, A.; Szadowska, A. 1989: The responsiveness of central benzodiazepine and GABA(A) receptors in vasopressin and spontaneously hypertensive rats Polish Journal of Pharmacology and Pharmacy 41(6): 629-637Tehrani, M.H.; Barnes, E.M. 1997: Sequestration of gamma-aminobutyric acidA receptors on clathrin-coated vesicles during chronic benzodiazepine administration in vivo Journal of Pharmacology and Experimental Therapeutics 283(1): 384-390
Rocca, P.; Ravizza, L.; Maina, G.; Bergamasco, B.; Ferrero, P. 1992: Peripheral-type benzodiazepine receptors in blood cells of anxious patients Advances in Biochemical Psychopharmacology 47: 229-233
Fuxe, K.; Köhler, C.; Agnati, L.F.; Andersson, K.; Ogren, S.O.; Eneroth, P.; Pérez de la Mora, M.; Karobath, M.; Krogsgaard-Larsen, P. 1981: GABA and benzodiazepine receptors. Studies on their localization in the hippocampus and their interaction with central dopamine neurons in the rat brain Advances in Biochemical Psychopharmacology 26: 61-76
Olson, J.M.; Junck, L.; Young, A.B.; Penney, J.B.; Mancini, W.R. 1988: Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging Cancer Research 48(20): 5837-5841
Anholt, R.R.; De Souza, E.B.; Oster-Granite, M.L.; Snyder, S.H. 1985: Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats Journal of Pharmacology and Experimental Therapeutics 233(2): 517-526
Andronati, S.A.; Chepelev, V.M.; Iakubovskaia, L.N.; Val'dman, A.V.; Voronina, T.A. 1983: Relationship between the structure, affinity to benzodiazepine receptors and properties of 5-halogenophenyl-1,2-dihydro-3H-1,4- benzodiazepine-2-ones Bioorganicheskaia Khimiia 9(10): 1357-1361
Squires, R.F.; Klepner, C.A.; Benson, D.I. 1980: Multiple benzodiazepine receptor complexes: some benzodiazepine recognition sites are coupled to GABA receptors and ionophores Advances in Biochemical Psychopharmacology 21: 285-293
Lowenstein, P.R.; González Solveyra, C.; Cardinali, D.P. 1984: Micromolar benzodiazepine binding sites of central type characteristics are present in the cerebral cortex of the rat Acta Physiologica et Pharmacologica Latinoamericana: Organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia 34(4): 441-443
Sieghart, W.; Drexler, G.; Mayer, A.; Schuster, A. 1983: Interaction of benzodiazepine agonists and antagonists with different benzodiazepine receptors Advances in Biochemical Psychopharmacology 38: 11-19
Sheppard, K.; Funder, J.W. 1987: Type I receptors in parotid, colon, and pituitary are aldosterone selective in vivo American Journal of Physiology 253(4 Pt 1): E467-E471
Shpakov, A.O. 1997: Sequence homology in the primary structures of tyrosine kinase receptors of insulin superfamily and protein substrates of insulin type i and type Ii receptors Ukrainskii Biokhimicheskii Zhurnal 69(4): 39-48
Tallman, J.F.; Gallager, D.W.; Mallorga, P.; Thomas, J.W.; Strittmatter, W.; Hirata, F.; Axelrod, J. 1980: Studies on benzodiazepine receptors Advances in Biochemical Psychopharmacology 21: 277-283
Sethy, V.H.; Russell, R.R.; Daenzer, C.L. 1983: Interaction of triazolobenzodiazepines with benzodiazepine receptors Journal of Pharmacy and Pharmacology 35(8): 524-526
Alexander, B.E.; Klotz, U. 1993: Peripheral benzodiazepine receptors and their possible biological role Die Pharmazie 48(8): 563-570
Stoebner, P.; Cano, J.; Meynadier, J.; Meunier, L. 2000: Cutaneous expression of peripheral benzodiazepine receptors Annales de Dermatologie et de Venereologie 127(4): 447-448
Young, W.S.; Kuhar, M.J. 1980: Radiohistochemical localization of benzodiazepine receptors in rat brain Journal of Pharmacology and Experimental Therapeutics 212(2): 337-346
Golovko, A.I.; Sofronov, G.A.; Kliuntina, T.V. 1993: N-methyl-3H]methylphenazepam--a new ligand for benzodiazepine receptors Biulleten' Eksperimental'noi Biologii i Meditsiny 115(4): 382-383
Hirsch, J.D.; Beyer, C.F.; Malkowitz, L.; Loullis, C.C.; Blume, A.J. 1989: Characterization of ligand binding to mitochondrial benzodiazepine receptors Molecular Pharmacology 35(1): 164-172
Butterworth, R.F. 1990: Brain GABA and benzodiazepine receptors in hepatic encephalopathy Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 42 Suppl: 137-140