An analysis of the gene coding for the basic neutralizing antigen VP7 of human rotavirus isolate 1407

Bessarab, I.N.; Epifanova, N.V.; Novikova, N.A.; Borodin, A.M.

Voprosy Virusologii 36(6): 480-483

1991


ISSN/ISBN: 0507-4088
PMID: 1664555
Document Number: 369214
A procedure based on polymerase chain reaction was developed for the study of rotaviruses. A full-length cDNA copy of the gene coding for major neutralizing glycoprotein VP7 of a human rotavirus isolate 1407 with the "long" electrophoretype (classified as the first electrophoretype) was cloned and sequenced. The primary structure of glycoprotein VP7 of isolate 1407 in A and C antigenic regions was found to be similar to that of serotype 1 virus.

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