Regulation of hysterectomy induced derangements in ovarian carbohydrate metabolism in albino rats. II. Role of prostaglandin F2 alpha
Umadevi, G.; Changamma, C.; Govindappa, S.
Indian Journal of Experimental Biology 29(11): 1067-1070
1991
ISSN/ISBN: 0019-5189 PMID: 1816086 Document Number: 368677
Wistar strain albino rats were subjected to bilateral hysterectomy surgically and the ovarian carbohydrate metabolism of these animals was compared with sham operated controls. The ovarian glycogen content of hysterectomized animals was elevated with inhibition of glycogenolysis, hexose mono and diphosphate pathways and oxidative metabolism. Administration of PGF2 alpha to hysterectomized animals led to activation of ovarian glycogenolysis and other pathways of carbohydrate metabolism of hysterectomized animals was restored towards normal level after PGF2 alpha substitution.