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Lipofuscin accumulation in the placenta in normal and gestosis-complicated pregnancy

Volkova, O.I.; Sidorova, I.S.

Akusherstvo i Ginekologiia 6: 13-17

1991

ISSN/ISBN: 0300-9092
PMID: 1951945
Document Number: 368522
Fluorescent microscopic examination of 20 placental samples from women in whom pregnancy ran a normal course and from those who suffered from gestosis was carried out to study lipofuscin accumulation in the placenta. Lipofuscin accumulation in the placenta was found to be a normal process, reflecting activation of lipid peroxidation. Placental lipofuscin accumulation was found higher in gestosis, this pointing to a reduction of the functional potentialities of the placenta. The maximum lipofuscin levels were detected in cases with gestosis associated with threatened abortion. Further investigation of this problem is necessary.

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