Anti-vascular antibodies in women with physiological pregnancy and pregnancy complicated by gestosis
Mel'nikov, V.A.; Kupaev, I.A.; Lipatov, I.S.
Akusherstvo i Ginekologiia 1992(3-7): 19-21
1992
ISSN/ISBN: 0300-9092 PMID: 1481956 Document Number: 404540
Immunologic manifestations of injury to the vascular wall were studied in 191 pregnant women. Blood serum ++anti-vascular antibodies were analyzed by passive hemagglutination, complement fixation, and precipitation tests. ++Anti-vascular antibodies were found in all the women with a normal pregnancy course. Normal pregnancy was characterized by clear-cut periods in the time course of ++anti-vascular antibody levels; for gestosis preclinical and clinical periods a constant growth of ++anti-vascular antibody titers was characteristics, that was due to effects of various injurious factors on the vascular wall. These data permit regarding gestosis as a vascular syndrome of pregnancy.