Human paraoxonase polymorphism: Hungarian population studies in children and adults
Szabó, I.; Róna, K.; Czinner, A.; Gachályi, B.
International Journal of Clinical Pharmacology Therapy and Toxicology 29(6): 238-241
1991
ISSN/ISBN: 0174-4879 PMID: 1651288 Document Number: 367840
The paraoxonase phenotype distribution pattern was studied in a Hungarian population of 102 children and 100 adults. All the subjects were of Caucasian origin and are not related. The adult population showed the trimodality in phenotype distribution similar to other European population data. The gene frequencies obtained were statistically not significantly different either. There was no correlation between the activity of serum paraoxonase and activity of cholinesterase, sex, age and body weight. The phenotype distribution was trimodal in the children's population too. There was a significant difference in gene frequency, however, compared to data from adult population.