Ultrasonographic assessment of urinary tract lesions due to Schistosoma haematobium in Niger after four consecutive years of treatment with praziquantel
Laurent, C.; Lamothe, F.; Develoux, M.; Sellin, B.; Mouchet, F.
Tropical Medicine and Parasitology Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit 41(2): 139-142
1990
ISSN/ISBN: 0177-2392 PMID: 2116659 Document Number: 367527
A comparative study on the extent of urinary tract abnormalities detected by ultrasound was conducted in two villages in an irrigated area of Niger where the pretreatment prevalences were 64.3% and 58.8% respectively. Fewer bladder lesions (20% of abnormalities) and fewer renal lesions (6% of abnormalities) were observed after four consecutive years of follow-up and treatment with praziquantel in the study village as compared to the control village where 54% bladder abnormalities and 36% renal abnormalities were observed. This study suggests that morbidity due to Schistosoma haematobium infection can be reduced by annual treatment over several years in a highly endemic area without other associated interventions.