Top Abstract Purchase Related
Home
>
Node
>
Subnode

Preformulation studies on suppositories by thermal methods

Giordano, F.; La Manna, A.; Bettinetti, G.P.; Zamparutti, M.

Bollettino Chimico Farmaceutico 129(4): 160-165

1990

ISSN/ISBN: 0006-6648
PMID: 2245004
Document Number: 367474
The application of differential scanning calorimetry (DSC) is described for investigating the interaction between trimethoprim and sulfamethoxypyridazine in suppository formulations containing fat bases (Suppocire, Novata, Witepsol). The thermal behavior of suppositories at various storage times is deeply influenced by the fat base and by interaction between active ingredients. Liquefaction time and dropping temperature were also evaluated for comparison and control purposes.

Document emailed within 1 workday
Secure & encrypted payments

Tantó, M.; Ecsy, Z.; Selmeczi, B.; Regdon, G. 1990: Biopharmaceutical study of aminophenazone-containing suppositories. 1. Experimental materials and methods, determination of physical qualities of the suppositories Acta Pharmaceutica Hungarica 60(4): 143-148
Horváth, G.; Nagy, K. 1994: Comparative in vitro dissolution studies of piroxicam suppositories using the basket, the paddle and the flow through methods Acta Pharmaceutica Hungarica 64(4): 135-140
Yao, Y.; Lin, G.; Xie, Y.; Ma, P.; Li, G.; Meng, Q.; Wu, T. 2014: Preformulation studies of myricetin: a natural antioxidant flavonoid Die Pharmazie 69(1): 19-26
Leuenberger, H.; Becher, W. 1975: A factorial design for compatibility studies on preformulation work Pharmaceutica Acta Helvetiae 50(4): 88-91
Ashizawa, K. 2006: Physicochemical profiling and preformulation studies at the drug discovery stage Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 127(3): 213-216
Algul, D.; Duman, G.; Ozdemir, S.; Acar, E.Turkoz.; Yener, G. 2018: Preformulation, Characterization, and In Vitro Release Studies of Caffeine-Loaded Solid Lipid Nanoparticles Journal of Cosmetic Science 69(3): 165-173
Rizzi, B.; Lodigiani, F.; Terni, E.; Chiavenna, F. 1979: A double-blind, proctoscopic and clinical comparison of flurbiprofen suppositories and ibuprofen suppositories in osteoarthrosis Panminerva Medica 21(4): 173-180
Doury, P. 1984: Comparative study of flurbiprofen 150 mg suppositories and diclofenac 100 mg suppositories in arthrosis Panminerva Medica 26(1): 55-56
Bornschein, M.; Hoffmann, K.; Voigt, R. 1985: Development and present status of methods for the determination of in vitro drug availability of suppositories Die Pharmazie 40(7): 449-455
Török, J.; Sallay, J.; Altmayer, P. 1982: Biopharmaceutical studies on vaginal suppositories containing antibiotics and antimycotics Die Pharmazie 37(8): 600-602
Terhaag, B.; le Petit, G.; Richter, K.; Rogner, M. 1985: In vitro and in vivo studies of diclofenac suppositories in humans Die Pharmazie 40(11): 784-786
Kanohta, K.; Abe, H. 1974: Studies on thermal natures of stationary phases for gas liquid chromatography. I. Thermal weight decrease of stationary phases Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences 49(92): 5-8
Szente, L.; Apostol, I.; Gerlóczy, A.; Szejtli, J. 1985: Suppositories containing cyclodextrin complexes. Part 2: Dissolution and absorption studies Die Pharmazie 40(6): 406-407
Sato, Y.; Iwata, S.; Akita, H.; Murai, T.; Ihara, M.; Oikawa, T.; Osano, M. 1985: Fundamental and clinical studies of ceftizoxime suppositories in the pediatric field Japanese Journal of Antibiotics 38(10): 2877-2888
Akai, Y.; Shiga, S.; Tohyama, K.; Shimatsu, A.; Ichiyama, S. 2000: Effect of heparin cofactor Ii on the antithrombin IIi activities measured by thrombin methods or factor Xa methods--fundamental studies and clinical studies using the plasma of pregnant women Rinsho Byori. Japanese Journal of Clinical Pathology 48(9): 867-871
Masiakowski, J.; Cieszyński, T.; Dyderski, S.; Perz, A. 1984: Biopharmaceutical evaluation of aminophylline suppositories. I. Pharmacological parameters of theophylline from aminophylline suppositories with normal and prolonged time of total deformation Acta Poloniae Pharmaceutica 41(1): 99-104
Vakulenko, G.A.; Pal'ti, A.M.; Arakelian, M.A. 1996: Thermal diagnostic methods in medicine Klinichna Khirurhiia 1996(11-12): 42-49
Sastri, M.S.; Satyanarayana, N.V.; Krishna, D.R.; Diwan, P.V. 1993: In vitro and in vivo studies on slow release propranolol hydrochloride suppositories. Pharmacokinetic and pharmacodynamic evaluation Arzneimittel-Forschung 43(3): 320-323
Finogenova, N.V.; Markova, O.V.; Mikhaĭlova, L.N.; Trusevich, Z.G. 1973: Methods in the quality control of the thermal treatment of meat products Gigiena i Sanitariia 38(10): 106
Legendre, B.; Guillot, F.; Pellerin, F. 1983: Quality control of irradiated plasticized polyvinyl chloride using thermal methods Annales Pharmaceutiques Francaises 41(4): 367-371