Analysis of the structure of the urban and rural populations of the central portion of Krasnodar Krai

Sladkova, S.V.; Revazov, A.A.; Golubtsov, V.I.; Kadoshnikova, M.I.

Genetika 26(11): 2070-2075


ISSN/ISBN: 0016-6758
PMID: 2150054
Document Number: 366823
To evaluate the pattern of Mendelian hereditary pathology in Krasnodav Krai, the demographic structure of two populations from the central part of Krasnodav Krai (Korenovsk and Ust'-Labinsk regions) was studied. THe age structure of the rural population was characterized by a predominance of the 47 year-old age group (0.406 compared with 0.262 and 0.332 for 0-18 and 19-46 year old age groups, respectively). The prevalence of an adult population resulted in the prevalence of autosome dominant diseases (0.92/1000, compared with 0.56/1000 for autosome recessive diseases). Family size and pregnancy outcomes were analyzed in 170 women who were past the reproductive age. Relatively small average family size (2.06) was indicative of active family planning regulated primarily by the means of induced abortions (3.69/woman). the length of generation calculated from the data on age-dependent fertility was 29.17 years for men and 19.12 years for women. The index of total selection calculated from the Crow index for pregnancy outcomes was 0.653, which was indicative of a less marked contribution of differential mortality and differential fertility to the intensity of natural selection. The endogamy indices for the urban populations of Korenovsk and Ust'-Labinsk regions were 0.174 and 0.195, respectively, while for the rural population of Ust'-Labinsk region, the endogamy index was 0.364. The gamete index for Korenovsk region was 0.142. The calculated values of gamete and endogamy indices were indicative of intensive migration processes, weak isolation by distance, and minimal inbreeding.

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