Vogt-Koyanagi-Harada syndrome and pregnancy

Steahly, L.P.

Annals of Ophthalmology 22(2): 59-62

1990


ISSN/ISBN: 0003-4886
PMID: 2316953
Document Number: 366427
Two black women had bilateral anterior and posterior uveitis, nonrhegmatogenous retinal detachments, pleocytosis, headaches, dysacousis, and alopecia. These patients with Vogt-Koyanagi-Harada (VKH) syndrome improved clinically while they were pregnant after the discontinuation of corticosteroid treatment. They developed recurrent symptoms and findings after termination of their pregnancies. We speculate that changes in immunity and humoral constituents during pregnancy account for their remissions. It is important to assess the menstrual history and to avoid pregnancy before initiating steroid treatment for VKH syndrome.

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