Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6
Lord, K.A.; Hoffman-Liebermann, B.; Liebermann, D.A.
Oncogene 5(7): 1095-1097
1990
ISSN/ISBN: 0950-9232 PMID: 2374694 Document Number: 365446
We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid precursors, following induction of terminal differentiation and growth arrest by IL6. Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-marrow, but not in several other non-myeloid murine tissues.
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