Generalized candidiasis in a prematurely born infant
Morpurgo, F.G.; Hack, W.W.; Ree, E.F.; Weyers, T.; van der Harten, J.J.; Taets van Amerongen, A.
Tijdschrift Voor Kindergeneeskunde 58(5): 179-182
1990
ISSN/ISBN: 0376-7442 PMID: 2247882 Document Number: 364581
A male neonate born after spontaneous labor during the 25 3/7 week of gestation, developed a fatal course of disseminated candidiasis. Disseminated candidiasis is seen in newborns undergoing intensive care and has a high mortality rate. Important etiologic factors are low immunologic response, invasive monitoring techniques, systemic antibiotics and parenteral nutrition. Early diagnosis and efficient antimycotic therapy with amphotericin B and if necessary combined with flucytosine contribute a great deal to the chance of survival.