Alpha 1-adrenoreceptor blockade and the molecular basis of lipid metabolism alterations

Pool, J.L.; Lenz, M.L.; Taylor, A.A.; Pool, J.L; Lenz, M.L; Taylor, A.A

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Alpha 1-adrenoreceptor blockade and the molecular basis of lipid metabolism alterations

Pool, J.L.; Lenz, M.L.; Taylor, A.A.

Journal of Human Hypertension 4(Suppl 3): 23-33

1990

ISSN/ISBN: 0950-9240

PMID: 1979818

Document Number: 362293

A study of doxazosin added to baseline therapy with a beta-adrenoceptor blocker plus a diuretic in the treatment of patients 'resistant' to the baseline therapy, showed that it was effective and generally well tolerated. The study was, however, open-label and lacked comparison with other third-line drugs.