Inhibition of erythrocyte ghost ATPase by polyene antibiotics
Capuozzo, E.; Jullien, S.; Salerno, C.; Crifò, C.
Biochemistry International 20(6): 1135-1139
1990
ISSN/ISBN: 0158-5231 PMID: 2164397 Document Number: 361678
The effect of micromolar concentrations of polyene antibiotics on erythrocyte ghost ATPase activities has been studied. (Mg2+)-ATPase is inhibited by amphotericin B and amphotericin B methyl ester, whereas (Na+ + K+ + Mg2+)-ATPase is inhibited by amphotericin B and lucensomycin. (Ca2+ + Mg2+)-ATPase is only slightly affected by polyene antibiotics.