Excretion of fluoxetine in human breast milk

Isenberg, K.E.

Journal of Clinical Psychiatry 51(4): 169

1990


ISSN/ISBN: 0160-6689
PMID: 2324084
Document Number: 361253
Following 2 months' treatment with 20 mg fluoxetine (an antidepressant) per day, blood plasma levels of 100.5 ng fluoxetine and 194.5 ng norfluoxetine (a metabolite presumed to be active) per ml were found. Corresponding levels in breast milk were 28.8 and 41.6 ng/ml. Thus nursing mothers treated with fluoxetine should be warned that the drug is excreted into breast milk.

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